Menaquinone-4-d7
Based on 1 Customer Validation
Menaquinone-4-d7 (Vitamin K2(MK-4)-d7) is the deuterium labeled Menaquinone-4. Menaquinone-4 is a vitamin K, used as a hemostatic agent, and also a adjunctive therapy for the pain of osteoporosis.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 97.84%
- No. CAS: 1233937-25-1
- Fòrmula: C31H33D7O2
- Peso molecular:451.69
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Almacenamiento:
-80°C, protect from light
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Actividad biológica
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Chemical Information
- Pureza y Documentación
- Referencias
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Help & FAQs
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Actividad biológica
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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No. CAS 1233937-25-1
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Unlabeled Cas 863-61-6
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Appearance Oil
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Peso molecular 451.69
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Fòrmula C31H33D7O2
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Color Light yellow to light brown
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SMILES
O=C1C=2C(C(=O)C(C([2H])([2H])[2H])=C1C/C=C(/CC/C=C(/CC/C=C(/CCC=C(C)C)\C)\C)\C)=C(C(=C(C2[2H])[2H])[2H])[2H]
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Synonyms
Vitamin K2(MK-4)-d7; Menaquinone K4-d7
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Envío
Shipping with dry ice.
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Almacenamiento
-80°C, protect from light
Pureza y Documentación
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Ficha de datos (264 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instrucciones de manejo (2659 KB)
Referencias
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Noda S, et al. Menaquinone-4 (vitamin K2) up-regulates expression of human intestinal alkaline phosphatase in Caco-2 cells. Nutr Res. 2016 Nov;36(11):1269-1276. [Content Brief]
[3]. Kim M, et al. Vitamin K1 (phylloquinone) and K2 (menaquinone-4) supplementation improves bone formation in a high-fat diet-induced obese mice. J Clin Biochem Nutr. 2013 Sep;53(2):108-13. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Menaquinone-4-d7 Related Classifications
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