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Evrisiran

Evrisiran is a prekallikrein synthesis reducer that has been studied for its potential use in hereditary angioedema.

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  • CAS No.: 3110420-82-8
  • 화학식: C498H665F8N162O313P43S8
  • 분자량:15668.86
  • 보관:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Evrisiran Chemical Structure
    Evrisiran Chemical Structure
CAS No.: 3110420-82-8
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All Kallikrein Isoforms

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  • Evrisiran Chemical Structure
    Evrisiran Chemical Structure RNA, ([1′-de(6-amino-9H-purin-9-yl)]A-(5′→5′)-sp-Um-Gm-Um-Cm-Am-Gm-Um-Um-(2′-deoxy-2′-fluoro)U-Um-(2′-deoxy-2′-fluoro)U-Cm-(2′-deoxy-2′-fluoro)A-Cm-Um-Um-Am-Um-Um-Cm-sp-Am-(3′→3′)-sp-[1′-de(6-amino-9H-purin-9-yl)]A), 3′-[O-[1-[18-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-6,10-bis[2-[[2-[2-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethyl]amino]-2-oxoethyl]-1,5,12-trioxo-16-oxa-6,10,13-triazaoctadec-1-yl]-4-piperidinyl] hydrogen phosphorothioate], complex with RNA (Um-[P(R)]-sp-(2′-deoxy-2′-fluoro)G-sp-Am-Am-Um-Am-(2′-deoxy-2′-fluoro)A-Gm-Um-Gm-Am-(2′-deoxy-2′-fluoro)A-Am-(2′-deoxy-2′-fluoro)A-Am-(2′-deoxy-2′-fluoro)C-Um-Gm-Am-sp-Cm-sp-Am) (1:1)
    1/16
  • RNA, ([1′-de(6-amino-9H-purin-9-yl)]A-(5′→5′)-sp-Um-Gm-Um-Cm-Am-Gm-Um-Um-(2′-deoxy-2′-fluoro)U-Um-(2′-deoxy-2′-fluoro)U-Cm-(2′-deoxy-2′-fluoro)A-Cm-Um-Um-Am-Um-Um-Cm-sp-Am-(3′→3′)-sp-[1′-de(6-amino-9H-purin-9-yl)]A), 3′-[O-[1-[18-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-6,10-bis[2-[[2-[2-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethyl]amino]-2-oxoethyl]-1,5,12-trioxo-16-oxa-6,10,13-triazaoctadec-1-yl]-4-piperidinyl] hydrogen phosphorothioate], complex with RNA (Um-[P(R)]-sp-(2′-deoxy-2′-fluoro)G-sp-Am-Am-Um-Am-(2′-deoxy-2′-fluoro)A-Gm-Um-Gm-Am-(2′-deoxy-2′-fluoro)A-Am-(2′-deoxy-2′-fluoro)A-Am-(2′-deoxy-2′-fluoro)C-Um-Gm-Am-sp-Cm-sp-Am) (1:1)