country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Referencia número: HY-146183

Copy Link Print Information

BCL6-IN-9

BCL6-IN-9 (compound 1) is a potent B-cell lymphoma 6 protein (BCL6) inhibitor, with an IC₅₀ of 3.9 nM. BCL6-IN-9 can be used for the research of cancer.

Para uso exclusivo en investigación. No vendemos a pacientes.

No. CAS: 2378852-76-5
Fòrmula: C₂₂H₁₈ClF₂N₅O₂
Peso molecular:457.86

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

BCL6-IN-9 Chemical Structure

No. CAS: 2378852-76-5

Tamaño

Precio

Stock

Cantidad

Amount: USD 0.00

* Seleccione Cantidad antes de agregar artículos.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- IC₅₀ & Target
- Cellular Effect
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

BCL6-IN-9 (compound 1) is a potent B-cell lymphoma 6 protein (BCL6) inhibitor, with an IC₅₀ of 3.9 nM. BCL6-IN-9 can be used for the research of cancer^[1].

IC₅₀ & Target

IC50: 3.9 nM (B-cell lymphoma 6 protein)^[1]

Ver todos los productos específicos de isoformas Bcl-2 Family :

Cellular Effect

Cell Line	Type	Value	Description	References
KARPAS-422	GI₅₀	0.19 μM Compound: 1	Antiproliferative activity against human KARPAS-422 cells assessed as cell growth inhibition mesured after 14 days by CellTiter-Glo luminescent assay Antiproliferative activity against human KARPAS-422 cells assessed as cell growth inhibition mesured after 14 days by CellTiter-Glo luminescent assay	[PMID: 35657291]
OCI-Ly1	GI₅₀	0.17 μM Compound: 1	Antiproliferative activity against human OCI-Ly1 cells assessed as cell growth inhibition mesured after 14 days by CellTiter-Glo luminescent assay Antiproliferative activity against human OCI-Ly1 cells assessed as cell growth inhibition mesured after 14 days by CellTiter-Glo luminescent assay	[PMID: 35657291]
OCI-Ly3	GI₅₀	3.4 μM Compound: 1	Antiproliferative activity against human OCILY3 cells assessed as cell growth inhibition mesured after 14 days by CellTiter-Glo luminescent assay Antiproliferative activity against human OCILY3 cells assessed as cell growth inhibition mesured after 14 days by CellTiter-Glo luminescent assay	[PMID: 35657291]

Chemical Information

No. CAS 2378852-76-5
Peso molecular 457.86
Fòrmula C₂₂H₁₈ClF₂N₅O₂
SMILES

N#CC1=C(NC2=CC3=C(N(C)C(C4=C3N[C@@H](C5CC5)C(F)(F)CO4)=O)C=C2)C=CN=C1Cl
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Davis OA, et, al. Optimizing Shape Complementarity Enables the Discovery of Potent Tricyclic BCL6 Inhibitors. J Med Chem. 2022 Jun 3. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

Obtener un presupuesto En stock

Other size

Obtener un presupuesto

Amount: USD 0.00

Actividad biológica
- Descripciòn
- IC₅₀ & Target
Chemical Information
Pureza y Documentación
Referencias

Nombre del producto:
Referencia número:
Cantidad:
MCE Japan Authorized Agent:

Nombre del producto:
No. CAS:
Species:
Pureza:
Cantidad:

BCL6-IN-9

Ver todos los productos específicos de isoformas Bcl-2 Family

Actividad biológica

Descripciòn

IC50 & Target

Cellular Effect

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

BCL6-IN-9 Related Classifications

HY-146183 Related Classifications

Bioz

Keywords

Your Recently Viewed Products

IC₅₀ & Target