CEP-8983
CEP-8983 is a PARP-1 and PARP-2 inhibitor (IC50: 20 and 6 nM). CEP-8983 is an effective chemosensitizing agent, and can sensitize chemotherapy-resistant cell lines and subcutaneous xenografts to Temozolomide (HY-17364) and Camptothecin (HY-16560).
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- No. CAS: 374071-46-2
- Fòrmula: C18H14N2O3
- Peso molecular:306.32
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Help & FAQs
Actividad biológica
Descripciòn
IC50 & Target
20 and 6 nM (PARP-1/2)[1].
Chemical Information
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No. CAS 374071-46-2
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Peso molecular 306.32
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Fòrmula C18H14N2O3
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SMILES
COC1=CC=CC2=C1C3=C(C(NC4=O)=O)C4=C(CCC5)C5=C3N2
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CEP-8983 Related Classifications
HY-14688 Related Classifications
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