Efmirenpase alfa
Efmirenpase alfa is an Fc-ENPP1 fusion protein (human IgG1 Fc domain linked to a modified human ENPP1). Efmirenpase alfa has prolonged half-life and enhanced receptor affinity compared with native human ENPP1. Efmirenpase alfa can be used as an enzyme replacement therapy for ENPP1 deficiency such as arterial calcification and hypophosphatemic rickets research.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 2770242-54-9
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
Isotype
human E-NPP1 fused via peptide linker to a human immunoglobulin G1 (IgG1) Fc fragment
Species Reactivity
Human
Ensayo clínico
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Conjugated
Unconjugated
Reconsititution
The product can be reconstituted/diluted with sterile PBS or saline.
Format
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FPIA_[PROTEIN]2-FC
Aplicación
ELISA, FACS, Functional assay
Chemical Information
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No. CAS 2770242-54-9
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SMILES
N/A
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Synonyms
INZ-701
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Efmirenpase alfa Related Classifications
HY-P991677 Related Classifications
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