Gpc1 - glypican 1 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14733

Summary

Enables Fibroblast Growth Factor binding activity and laminin binding activity. Involved in negative regulation of Fibroblast Growth Factor receptor signaling pathway. Acts upstream of or within positive regulation of skeletal muscle cell differentiation. Located in extracellular matrix; membrane raft; and synapse. Is expressed in several structures, including alimentary system; limb; metanephros; musculoskeletal system; and nervous system. Orthologous to human GPC1 (glypican 1). [provided by Alliance of Genome Resources, Apr 2022]

Gpc1 Products (1)

mRNA Protein Name
NM_016696.5 NP_057905.1 glypican-1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Referencias Source
enables fibroblast growth factor binding IDA
IDA: Inferred from direct assay
20100867 MGI
enables laminin binding IDA
IDA: Inferred from direct assay
20100867 MGI
Biological Process GO Annotation Evidence Referencias Source
involved in negative regulation of fibroblast growth factor receptor signaling pathway IDA
IDA: Inferred from direct assay
20100867 MGI
involved in positive regulation of skeletal muscle cell differentiation IEP
IEP: Inferred from expression pattern
20100867 MGI
Cellular Component GO Annotation Evidence Referencias Source
located in extracellular matrix IDA
IDA: Inferred from direct assay
20100867 MGI
located in membrane raft IDA
IDA: Inferred from direct assay
20100867 MGI
is active in synapse EXP
EXP: Inferred from Experiment
16452087 MGI
is active in synapse IDA
IDA: Inferred from direct assay
16452087 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glypican-1

Recombinant Gpc1 Proteins

Referencia número Nombre del producto Accession Pureza
HY-P70928 Glypican-1/GPC1 Protein, Mouse (HEK293, His) Q9QZF2 (D24-S529) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Referencia número Nombre del producto
Efecto
Pureza
Rare Diseases
HY-RS05626 GPC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-134225 1-O-Hexadecyl-2-arachidonoyl-sn-glycero-3-PC / Unkown
HY-RS18940 Gpc1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25430 Gpc1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Referencia número Nombre del producto
Efecto
Pureza
Rare Diseases
HY-P990841 Anti-pan-Glypican Antibody (HS20) Inhibitor 99.44% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gpc1 NCBI NCBI:2817