CPVL - carboxypeptidase vitellogenic like Gene
Also Known as HVLP
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 54504
About CPVL
Cytogenetic location: 7p14.3
Genomic coordinates (GRCh38): 7:28,994,636-29,195,451 (from NCBI)
This gene has 12 transcripts (splice variants), 193 orthologues and 2 paralogues. Broad expression in spleen (RPKM 87.7), thyroid (RPKM 67.4) and 23 other tissues.
Summary
The protein encoded by this gene is a Carboxypeptidase and bears strong sequence similarity to serine carboxypeptidases. Carboxypeptidases are a large class of proteases that act to cleave a single amino acid from the carboxy termini of proteins or peptides. The exact function of this protein, however, has not been determined. [provided by RefSeq, Jan 2017]
CPVL Products (17)
| mRNA | Protein | Name |
|---|---|---|
| NM_001348052.1 | NP_001334981.1 | probable serine carboxypeptidase CPVL isoform b precursor |
| NM_001348054.1 | NP_001334983.1 | probable serine carboxypeptidase CPVL isoform b precursor |
| NM_001371255.1 | NP_001358184.1 | probable serine carboxypeptidase CPVL isoform b precursor |
| NM_001371256.1 | NP_001358185.1 | probable serine carboxypeptidase CPVL isoform b precursor |
| NM_001371257.1 | NP_001358186.1 | probable serine carboxypeptidase CPVL isoform b precursor |
| NM_001371258.1 | NP_001358187.1 | probable serine carboxypeptidase CPVL isoform b precursor |
| NM_001371260.1 | NP_001358189.1 | probable serine carboxypeptidase CPVL isoform b precursor |
| NM_001371261.1 | NP_001358190.1 | probable serine carboxypeptidase CPVL isoform b precursor |
| NM_001371262.1 | NP_001358191.1 | probable serine carboxypeptidase CPVL isoform b precursor |
| NM_001371263.1 | NP_001358192.1 | probable serine carboxypeptidase CPVL isoform b precursor |
| NM_001371264.1 | NP_001358193.1 | probable serine carboxypeptidase CPVL isoform a precursor |
| NM_001371265.1 | NP_001358194.1 | probable serine carboxypeptidase CPVL isoform c |
| NM_001371266.1 | NP_001358195.1 | probable serine carboxypeptidase CPVL isoform c |
| NM_001371267.1 | NP_001358196.1 | probable serine carboxypeptidase CPVL isoform c |
| NM_001371268.1 | NP_001358197.1 | probable serine carboxypeptidase CPVL isoform d |
| NM_019029.3 | NP_061902.2 | probable serine carboxypeptidase CPVL isoform b precursor |
| NM_031311.5 | NP_112601.3 | probable serine carboxypeptidase CPVL isoform b precursor |
CPVL Protein Structure
Peptidase_S10
Peptidase_S10: Serine carboxypeptidase (69 - 467)
- 0
- 100
- 200
- 300
- 400
- 476 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
probable serine carboxypeptidase CPVL |
|
Recombinant CPVL Proteins
| Referencia número | Nombre del producto | Accession | Pureza |
|---|---|---|---|
| HY-P7818 | CPVL Protein, Human (HEK293, His) | AAH16838.1 (L23-G476) | ≥ 95%, as determined by reducing SDS-PAGE. |
CPVL Antibodies
| Referencia número | Nombre del producto | Aplicación | Reactivity |
|---|---|---|---|
| HY-P86298 | CPVL Antibody (YA5990) | WB, IHC-P | Human |
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Noonan Syndrome 6 |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(3)
| Referencia número | Nombre del producto |
Efecto
|
Pureza |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS03127 | CPVL Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS20709 | Cpvl Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS27220 | Cpvl Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Bos taurus | CPVL | VGNC | VGNC:58370 |
| Macaca mulatta | CPVL | VGNC | VGNC:71406 |
| Mus musculus | CPVL | MGD | MGI:1918537 |
| Canis familiaris | CPVL | VGNC | VGNC:39584 |
| Felis catus | CPVL | VGNC | VGNC:61150 |
| Rattus norvegicus | CPVL | RGD | RGD:1563609 |
| Others | CPVL | NCBI |
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