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Referencia número: HY-169788

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Graveolinine

Graveolinine is a quinoline alkaloid, that can be isolated from Ruta chalepensis. Graveolinine exhibits antiplatelet activity, that reduces Arachidonic Acid (HY-109590)- and Collagen-induced aggregation of washed rabbit platelets.

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No. CAS: 4179-37-7
Fòrmula: C₁₇H₁₃NO₃
Peso molecular:279.29

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Graveolinine Chemical Structure

No. CAS: 4179-37-7

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- Cellular Effect
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

Cellular Effect

Cell Line	Type	Value	Description	References
HepG2	IC₅₀	>50 μM Compound: Graveolinine	Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 31744779]
PC-12	IC₅₀	>50 μM Compound: Graveolinine	Cytotoxicity against rat PC12 cells assessed as growth inhibition after 48 hrs by MTT assay Cytotoxicity against rat PC12 cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 31744779]

Chemical Information

No. CAS 4179-37-7
Peso molecular 279.29
Fòrmula C₁₇H₁₃NO₃
SMILES

COC1=CC(C2=CC3=C(OCO3)C=C2)=NC4=C1C=CC=C4
Structure Classification
- Alkaloids
- Quinoline Alkaloids
Initial Source
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Ulubelen A, et al., Alkaloids and coumarins from the roots of Ruta chalepensis var. latifolia. Planta Med. 1988 Dec;54(6):551-2. [Content Brief]

[2]. Wu T S, et al. Cytotoxic and antiplatelet aggregation principles of Ruta graveolens[J]. Journal of the Chinese chemical society, 2003, 50(1): 171-178.

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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