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United States

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Referencia número: HY-P12378

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HTTIPKV

HTTIPKV is a CAF-selective peptide. HTTIPKV specifically binds to recombinant TAS2R9. HTTIPKV selectively localizes to cancer-associated fibroblasts and the stroma of pancreatic ductal adenocarcinoma. Conjugation of HTTIPKV to liposomes enhances tumor accumulation and improves delivery of encapsulated CXCR2 inhibitors, thereby reducing tumor growth. HTTIPKV can be used for research on pancreatic ductal adenocarcinoma.

Para uso exclusivo en investigación. No vendemos a pacientes.

Fòrmula: C₃₆H₆₂N₁₀O₁₀
Peso molecular:794.94

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

HTTIPKV Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica

Descripciòn

Chemical Information

Peso molecular 794.94
Fòrmula C₃₆H₆₂N₁₀O₁₀
SMILES

O=C(N[C@@H]([C@H](O)C)C(N[C@@H]([C@H](O)C)C(N[C@@H]([C@@H](C)CC)C(N1[C@@H](CCC1)C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(O)=O)=O)=O)=O)=O)=O)[C@H](CC2=CNC=N2)N
Sequence

His-Thr-Thr-Ile-Pro-Lys-Val
Sequence Shortening

HTTIPKV
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. Hung J, et al. A Bitter Taste Receptor as a Novel Molecular Target on Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma. Pharmaceuticals (Basel, Switzerland). 2023 Mar 03;16(3):389.

[2]. Yang Y, et al. Targeting tumor stroma via ultrasound-activated nanodroplets: Disrupting exosome-driven microenvironment crosstalk for enhanced antitumor efficacy. Journal of controlled release : official journal of the Controlled Release Society. 2025 Oct 10;386:114113.

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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