KI 1769
KI 1769 is a potassium channel opener. KI 1769 can exhibit vasodilating effect. KI 1769 prolongs the micturition interval and reduces the resistance to fluid infusion through the urethral lumen. KI 1769 can be used for the research of cardiovascular disease.
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- No. CAS: 133300-00-2
- Fòrmula: C15H14N4
- Peso molecular:250.30
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Descripciòn
In Vivo
KI 1769 (0.3 mg/kg, i.v.) prolongs the micturition interval and reduces the resistance to fluid infusion through the urethral lumen in rats[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 133300-00-2
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Peso molecular 250.30
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Fòrmula C15H14N4
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SMILES
N#CN/C(C1=CC=CN=C1)=N/CCC2=CC=CC=C2
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Izumi H, et al. In vitro and in vivo vasodilating effects of KRN4884, Ki1769 and Ki3005, pyridinecarboxamidine derivatives. Fundam Clin Pharmacol. 1997;11(6):561-6. [Content Brief]
[2]. Kontani H, et al. Effect of K+ channel openers, KRN2391 and Ki1769, and nitroglycerin on the urinary tract of rats in vivo. Jpn J Pharmacol. 1999 Jun;80(2):143-53. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)