LNK2-S
Based on 1 Customer Validation
LNK2-S is a conjugated compound of toxin molecule Exatecan (HY-13631) and Linker, which can be used to synthesize ADC molecule.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 96.49%
- No. CAS: 2983134-61-6
- Fòrmula: C87H112FN19O33
- Peso molecular:1970.93
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Almacenamiento:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Actividad biológica
Descripciòn
Chemical Information
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No. CAS 2983134-61-6
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Appearance Solid
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Peso molecular 1970.93
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Fòrmula C87H112FN19O33
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Color Light yellow to yellow
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SMILES
O=C([C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](OC2=CC=C([C@@H](CNC(CC[C@H](NC(COCCOCCNC(CCN3C(C=CC3=O)=O)=O)=O)C(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)OC(N[C@H]4CCC5=C6C4=C(CN7C(C(COC([C@@]8(CC)O)=O)=C8C=C79)=O)C9=NC6=CC(F)=C5C)=O)C=C2[N+]([O-])=O)O1)O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvente y solubilidad
In Vitro:
DMSO : 100 mg/mL (50.74 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.5074 mL | 2.5369 mL | 5.0737 mL | 12.6844 mL |
| 5 mM | 0.1015 mL | 0.5074 mL | 1.0147 mL | 2.5369 mL | |
| 10 mM | 0.0507 mL | 0.2537 mL | 0.5074 mL | 1.2684 mL | |
| 15 mM | 0.0338 mL | 0.1691 mL | 0.3382 mL | 0.8456 mL | |
| 20 mM | 0.0254 mL | 0.1268 mL | 0.2537 mL | 0.6342 mL | |
| 25 mM | 0.0203 mL | 0.1015 mL | 0.2029 mL | 0.5074 mL | |
| 30 mM | 0.0169 mL | 0.0846 mL | 0.1691 mL | 0.4228 mL | |
| 40 mM | 0.0127 mL | 0.0634 mL | 0.1268 mL | 0.3171 mL | |
| 50 mM | 0.0101 mL | 0.0507 mL | 0.1015 mL | 0.2537 mL |