NAIA
NAIA (N-Acryloylindole-alkyne) is a cysteine-reactive probe. NAIA can be used as an imaging agent, proteome profiling agent, and covalent ligand screening tool.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 3020685-33-7
- Fòrmula: C19H20N2O3
- Peso molecular:324.37
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Actividad biológica
-
Chemical Information
- Pureza y Documentación
- Referencias
-
Help & FAQs
Actividad biológica
Descripciòn
In Vitro
NAIA enables proteome-wide identification of functional cysteines in HepG2 cell lysates via MS-based ABPP[2].
NAIA enables functional cysteine profiling in live cells and cancer cell lysates[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
-
No. CAS 3020685-33-7
-
Peso molecular 324.37
-
Fòrmula C19H20N2O3
-
SMILES
O=C(N1C=CC2=C1C=CC(OCC(NCCCCC#C)=O)=C2)C=C
-
Synonyms
N-Acryloylindole-alkyne
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Koo TY, et al. N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. [Content Brief]
[2]. Koo TY, et al. Activity-Based Protein Profiling for Functional Cysteines and Protein Target Identification. Methods Mol Biol. 2025;2921:331-344. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NAIA Related Classifications
HY-183740 Related Classifications
Powered by Bioz