3020685-33-7
3020685-33-7
Chemical Structure
NAIA
Synonym(s): N-Acryloylindole-alkyne
- CAS. Nr.: 3020685-33-7
- Formula:C19H20N2O3
- Molecular Weight:324.37
InChIKey: STJKPWRTQBLLKC-UHFFFAOYSA-N
SMILES: O=C(N1C=CC2=C1C=CC(OCC(NCCCCC#C)=O)=C2)C=C
Biological Activity: NAIA (N-Acryloylindole-alkyne) is a cysteine-reactive probe. NAIA can be used as an imaging agent, proteome profiling agent, and covalent ligand screening tool[1][2].
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NAIA | NAIA (N-Acryloylindole-alkyne) is a cysteine-reactive probe. NAIA can be used as an imaging agent, proteome profiling agent, and covalent ligand screening tool. | |||||||||||||||||||||
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References
- [1]. Koo TY, et al. N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. [Content Brief]
- [2]. Koo TY, et al. Activity-Based Protein Profiling for Functional Cysteines and Protein Target Identification. Methods Mol Biol. 2025;2921:331-344. [Content Brief]
