NAIA
NAIA (N-Acryloylindole-alkyne) is a cysteine-reactive probe. NAIA can be used as an imaging agent, proteome profiling agent, and covalent ligand screening tool.
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- CAS. Nr.: 3020685-33-7
- Formel: C19H20N2O3
- Molecular Weight:324.37
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Beschreibung
In Vitro
NAIA enables proteome-wide identification of functional cysteines in HepG2 cell lysates via MS-based ABPP[2].
NAIA enables functional cysteine profiling in live cells and cancer cell lysates[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS. Nr. 3020685-33-7
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Molecular Weight 324.37
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Formel C19H20N2O3
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SMILES
O=C(N1C=CC2=C1C=CC(OCC(NCCCCC#C)=O)=C2)C=C
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Synonyms
N-Acryloylindole-alkyne
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Koo TY, et al. N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. [Content Brief]
[2]. Koo TY, et al. Activity-Based Protein Profiling for Functional Cysteines and Protein Target Identification. Methods Mol Biol. 2025;2921:331-344. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
NAIA Related Classifications
HY-183740 Related Classifications
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