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Referencia número: HY-N11141

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(R)-Octopamine

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(R)-Octopamine is a Gs-coupled receptor agonist. (R)-Octopamine binds to the orthosteric site of BmOAR2 and interacts with the Asp115, Ser202 and Tyr300 residues to activate the receptor, which couples to Gs protein and thereby stimulates adenylate cyclase activity.

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Pureza: 95.22%
No. CAS: 876-04-0
Fòrmula: C₈H₁₁NO₂
Peso molecular:153.18

Almacenamiento:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

(R)-Octopamine Chemical Structure

No. CAS: 876-04-0

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Actividad biológica

Descripciòn

Ver todos los productos específicos de isoformas Adrenergic Receptor :

In Vitro

(R)-Octopamine (0.1 nM-10 μM; 20 min after IBMX preincubation) potently activates wild-type BmOAR2 in HEK-293 cells to elevate intracellular cAMP levels, with an EC₅₀ of approximately 1.0 nM and maximum response at 10 nM^[1].
(R)-Octopamine interacts with BmOAR2 via hydrogen bonds between its phenolic OH group and Ser202/Tyr300, and between its NH₂/β-OH groups and Asp115^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 876-04-0
Appearance Solid
Peso molecular 153.18
Fòrmula C₈H₁₁NO₂
Color White to light yellow
SMILES

NC[C@@H](C1=CC=C(C=C1)O)O
Structure Classification
- Phenols
- Monophenols
Initial Source
- Endogenous metabolite
Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Pureza y Documentación

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Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (266 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Xi Chen, et al. Amino acid residues involved in the interaction with the intrinsic agonist (R)-octopamine in the .BETA.-adrenergic-like octopamine receptor from the silkworm Bombyx mori. Journal of Pesticide Science 36(4):473-480.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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(R)-Octopamine

High-Throughput Bioactive Compound Library

Ver todos los productos específicos de isoformas Adrenergic Receptor

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(R)-Octopamine Related Classifications

HY-N11141 Related Classifications