Riodipine
Riodipine (PP-1466) is a vasodilator. Riodipine can be used for the research of antihypertensive.
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- No. CAS: 71653-63-9
- Fòrmula: C18H19F2NO5
- Peso molecular:367.34
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
IC50 & Target
Riodipine;Foridon;PP 1466;PP1466;PP-1466
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | EC50 |
1.6 μM
Compound: Riodipine
|
Activation of human PXR expressed in human HepG2 (DPX-2) cells assessed as induction of CYP3A4 after 24 hrs by luminescent analysis
Activation of human PXR expressed in human HepG2 (DPX-2) cells assessed as induction of CYP3A4 after 24 hrs by luminescent analysis
|
[PMID: 20966043] |
| HepG2 | EC50 |
1.8 μM
Compound: Riodipine
|
Activation of rat PXR expressed in human HepG2 cells after 24 hrs by luciferase reporter gene based luminescent analysis
Activation of rat PXR expressed in human HepG2 cells after 24 hrs by luciferase reporter gene based luminescent analysis
|
[PMID: 20966043] |
| HepG2 | EC50 |
4 μM
Compound: Riodipine
|
Activation of human PXR expressed in human HepG2 (DPX-2) cells after 24 hrs by luciferase reporter gene based luminescent analysis
Activation of human PXR expressed in human HepG2 (DPX-2) cells after 24 hrs by luciferase reporter gene based luminescent analysis
|
[PMID: 20966043] |
Chemical Information
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No. CAS 71653-63-9
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Peso molecular 367.34
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Fòrmula C18H19F2NO5
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SMILES
O=C(OC)C1=C(NC(C)=C(C1C2=CC=CC=C2OC(F)F)C(OC)=O)C
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Synonyms
Foridon; PP-1466
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)