1. Gene
  2. CDH9 - cadherin 9 Gene

CDH9 - cadherin 9 Gene

Homo sapiens
Gene ID: 1007 | Gene type: protein coding

About CDH9

Cytogenetic location: 5p14.1 Genomic coordinates (GRCh38): 5:26,880,597-27,038,586 (from NCBI)

This gene has 5 transcripts (splice variants), 133 orthologues and 33 paralogues. Biased expression in brain (RPKM 3.5) and kidney (RPKM 1.9).

Summary

This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) Cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I Cadherins. [provided by RefSeq, Jul 2008]

CDH9 Products(1)

mRNA Protein Name
NM_016279.4 NP_057363.3 cadherin-9 preproprotein

CDH9 Protein Structure

Cadherin

Cadherin: Cadherin domain (68 - 147)

Cadherin

Cadherin: Cadherin domain (164 - 258)

Cadherin

Cadherin: Cadherin domain (273 - 359)

Cadherin

Cadherin: Cadherin domain (388 - 478)

Cadherin

Cadherin: Cadherin domain (492 - 589)

Cadherin_C

Cadherin_C: Cadherin cytoplasmic region (639 - 783)

  • 0
  • 200
  • 400
  • 600
  • 789 a.a.
Protein Preferred Names Protein Names

cadherin-9

T1-cadherin

Recombinant CDH9 Proteins

Cat. No. Product Name Accession Purity
HY-P79440 Cadherin-9 Protein, Human (HEK293, hFc) Q9ULB4 (G54-A615) ≥95%

Related Diseases

Diseases Alias
Craniofacial-Deafness-Hand Syndrome

CDHS

Craniofacial Deafness Hand Syndrome

Sommer-Young-Wee-Frye Syndrome

Features Of Flat Facial Profile, Hypertelorism, Hypoplastic Nose With Slitlike Nares, And A Sensorineural Hearing Loss

Craniofacial-Hearing Loss-Hand Syndrome

Childhood Disintegrative Disease

Childhood Disintegrative Disorder

Disintegrative Psychosis

Heller'S Syndrome

Symbiotic Psychosis

Dementia Infantilis

Heller Syndrome

Shared Paranoid Disorder

Autism

Autistic Disorder

Autism Susceptibility 1

Childhood Autism

Autistic Disorder Of Childhood Onset

Infantile Autism

Kanner'S Syndrome

Autistic

Benign Epilepsy With Centrotemporal Spikes

Rolandic Epilepsy

Benign Rolandic Epilepsy

Epilepsy, Rolandic

Bcects

Benign Childhood Epilepsy With Centrotemporal Spike

Sylvan Seizures

Becrs

Bects

Bre

Benign Epilepsy Of Childhood With Centrotemporal Spikes

Benign Familial Epilepsy Of Childhood With Rolandic Spikes

Centrotemporal Epilepsy

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Bos taurus CDH9 VGNC VGNC:27107
Mus musculus CDH9 MGD MGI:107433
Felis catus CDH9 VGNC VGNC:60687
Macaca mulatta CDH9 VGNC VGNC:70977
Canis familiaris CDH9 VGNC VGNC:39036
Rattus norvegicus CDH9 RGD RGD:1308343