CDH9 - cadherin 9 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 1007

About CDH9

Cytogenetic location: 5p14.1 Genomic coordinates (GRCh38): 5:26,880,597-27,038,586 (from NCBI)

This gene has 5 transcripts (splice variants), 133 orthologues and 33 paralogues. Biased expression in brain (RPKM 3.5) and kidney (RPKM 1.9).

Summary

This gene encodes a type II classical Cadherin from the Cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature Cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a Cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) Cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I Cadherins. [provided by RefSeq, Jul 2008]

CDH9 Products (1)

mRNA Protein Name
NM_016279.4 NP_057363.3 cadherin-9 preproprotein

CDH9 Protein Structure

Cadherin

Cadherin: Cadherin domain (68 - 147)

Cadherin

Cadherin: Cadherin domain (164 - 258)

Cadherin

Cadherin: Cadherin domain (273 - 359)

Cadherin

Cadherin: Cadherin domain (388 - 478)

Cadherin

Cadherin: Cadherin domain (492 - 589)

Cadherin_C

Cadherin_C: Cadherin cytoplasmic region (639 - 783)

  • 0
  • 200
  • 400
  • 600
  • 789 a.a.
Protein Preferred Names Protein Names

cadherin-9

  • T1-cadherin

Recombinant CDH9 Proteins

Cat. No. Product Name Accession Purity
HY-P78770 Cadherin-9/CDH9 Protein, Human (HEK293, His) Q9ULB4-1 (G54-A615) ≥ 90%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Craniofacial-Deafness-Hand Syndrome

  • CDHS

  • Craniofacial Deafness Hand Syndrome

  • Sommer-Young-Wee-Frye Syndrome

  • Features Of Flat Facial Profile, Hypertelorism, Hypoplastic Nose With Slitlike Nares, And A Sensorineural Hearing Loss

  • Craniofacial-Hearing Loss-Hand Syndrome
Childhood Disintegrative Disease

  • Childhood Disintegrative Disorder

  • Disintegrative Psychosis

  • Heller'S Syndrome

  • Symbiotic Psychosis

  • Dementia Infantilis

  • Heller Syndrome

  • Shared Paranoid Disorder
Autism

  • Autistic Disorder

  • Autism Susceptibility 1

  • Childhood Autism

  • Autistic Disorder Of Childhood Onset

  • Infantile Autism

  • Kanner'S Syndrome

  • Autistic
Benign Epilepsy With Centrotemporal Spikes

  • Rolandic Epilepsy

  • Benign Rolandic Epilepsy

  • Epilepsy, Rolandic

  • Bcects

  • Benign Childhood Epilepsy With Centrotemporal Spike

  • Sylvan Seizures

  • Becrs

  • Bects

  • Bre

  • Benign Epilepsy Of Childhood With Centrotemporal Spikes

  • Benign Familial Epilepsy Of Childhood With Rolandic Spikes

  • Centrotemporal Epilepsy
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02342 CDH9 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus CDH9 VGNC VGNC:27107
Mus musculus CDH9 MGD MGI:107433
Felis catus CDH9 VGNC VGNC:60687
Macaca mulatta CDH9 VGNC VGNC:70977
Canis familiaris CDH9 VGNC VGNC:39036
Rattus norvegicus CDH9 RGD RGD:1308343
Others CDH9 NCBI