CD96 - CD96 molecule Gene

Homo sapiens

Also known as TACTILE

Gene ID: 10225 | Gene type: protein coding

About CD96

Cytogenetic location: 3q13.13-q13.2 Genomic coordinates (GRCh38): 3:111,542,197-111,665,996 (from NCBI)

This gene has 7 transcripts (splice variants), 106 orthologues and is associated with 3 phenotypes. Broad expression in lymph node (RPKM 4.8), appendix (RPKM 2.7) and 15 other tissues.

Summary

The protein encoded by this gene belongs to the immunoglobulin superfamily. It is a type I membrane protein. The protein may play a role in the adhesive interactions of activated T and NK cells during the late phase of the immune response. It may also function in antigen presentation. Alternative splicing generates multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2016]

CD96 Products(4)

mRNA	Protein	Name
NM_001318889.2	NP_001305818.1	T-cell surface protein tactile isoform 3
NM_001410800.1	NP_001397729.1	T-cell surface protein tactile isoform 4
NM_005816.5	NP_005807.1	T-cell surface protein tactile isoform 2 precursor
NM_198196.3	NP_937839.1	T-cell surface protein tactile isoform 1 precursor

CD96 Protein Structure

Ig_2

Ig_3

0
100
200
300
400
500
585 a.a.

Protein Preferred Names

Protein Names

T-cell surface protein tactile

T cell activation, increased late expression

Recombinant CD96 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P72698	CD96 Protein, Human (HEK293, His)	P40200-2 (V22-M503)	≥95%
HY-P75371	CD96 Protein, Human (Biotinylated, HEK293, His)	P40200-2 (V22-M503)	≥95%
HY-P75372	CD96 Protein, Human (503a.a, HEK293, His)	P40200-2 (M1-M503)	≥95%
HY-P78420	CD96 Protein, Human (HEK293, mFc)	P40200-2 (V22-M503)	≥95%
HY-P78660	CD96 Protein, Human (C110S, HEK293, His)	P40200-2 (V22-M503, C110S)	≥95%
HY-P700855	CD96 Protein, Human (Biotinylated, HEK293, His-Avi)	P40200-2 (V22-M503)	≥95%

Related Diseases

Diseases

Alias

C Syndrome

Opitz Trigonocephaly Syndrome	Trigonocephaly
Trigonocephaly Syndrome	Trigonocephaly C Syndrome
Opitz C Trigonocephaly	Opitz Trigonocephaly C Syndrome
Otcs	CSYN

Leukemia, Acute Myeloid

Acute Myeloid Leukemia	Leukemia, Acute Myelogenous
Acute Myelogenous Leukemia	AML
Leukemia, Acute Myeloid, Susceptibility To	Acute Myeloblastic Leukemia
Leukemia, Acute Myeloid, Reduced Survival In, Somatic	Acute Myeloid Leukaemia
Leukemia, Myelocytic, Acute	Therapy Related Acute Myeloid Leukemia And Myelodysplastic Syndrome
Secondary Aml	Acute Myelocytic Leukemia
Acute Myeloid Leukemia, Somatic	Leukemia, Acute Myeloid, Somatic
Myeloid Leukemia, Acute, M4/M4eo Subtype, Somatic	Acute Myeloblastic Leukaemia
Acute Myelogenous Leukaemia	Aml - Acute Myeloid Leukemia
Acute Myeloid Leukemia With Cebpa Somatic Mutations	Aml With Cebpa Somatic Mutations
Inherited Acute Myeloid Leukemia	Familial Aml
Inherited Aml	Pure Familial Aml
Pure Familial Acute Myeloid Leukemia	Secondary Acute Myeloid Leukemia
Therapy-Related Aml And Myelodysplastic Syndrome	Acute Myeloid Leukemia, Secondary
Acute Non-Lymphoblastic Leukemia	Acute Non-Lymphocytic Leukemia
Acute Biphenotypic Leukemia	Acute Undifferentiated Leukemia
Acute Myeloblastic Leukaemia With Multilineage Dysplasia	Acute Myeloid Leukaemia With Multilineage Dysplasia Without Mention Of Remission
Acute Myeloid Leukaemia With Myelodysplasia-Related Features

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02279	CD96 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	CD96	VGNC	VGNC:102640
Bos taurus	CD96	VGNC	VGNC:27054
Canis familiaris	CD96	VGNC	VGNC:38982
Rattus norvegicus	CD96	RGD	RGD:1565249
Macaca mulatta	CD96	VGNC	VGNC:70773
Mus musculus	CD96	MGD	MGI:1934368
Macaca fascicularis	CD96	NCBI
Others	CD96	NCBI