Pls3 - plastin 3 (T-isoform) Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 102866

Summary

A structural constituent of presynaptic actin Cytoskeleton. Involved in regulation of synaptic vesicle cycle. Located in cytoplasm. Is active in neuromuscular junction. Is expressed in egg cylinder; female reproductive system; forebrain; and gut. Human ortholog(s) of this gene implicated in osteoporosis. Orthologous to human PLS3 (plastin 3). [provided by Alliance of Genome Resources, Apr 2022]

Pls3 Products (5)

mRNA Protein Name
NM_001166453.1 NP_001159925.1 plastin-3 isoform 1
NM_001166454.2 NP_001159926.1 plastin-3 isoform 1
NM_001346519.1 NP_001333448.1 plastin-3 isoform 2
NM_001346520.1 NP_001333449.1 plastin-3 isoform 2
NM_145629.2 NP_663604.1 plastin-3 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables structural constituent of presynaptic actin cytoskeleton IDA
IDA: Inferred from direct assay
23263861 MGI
enables structural constituent of presynaptic actin cytoskeleton IMP
IMP: Inferred from mutant phenotype
23263861 MGI
Biological Process GO Annotation Evidence References Source
involved in regulation of synaptic vesicle cycle IDA
IDA: Inferred from direct assay
23263861 MGI
involved in regulation of synaptic vesicle cycle IMP
IMP: Inferred from mutant phenotype
23263861 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
7655078 MGI
is active in neuromuscular junction IDA
IDA: Inferred from direct assay
23263861 MGI
is active in neuromuscular junction IMP
IMP: Inferred from mutant phenotype
23263861 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

plastin-3

  • T-fimbrin

  • T-plastin

  • plastin 3, T

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10740 PLS3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18493 Pls3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24975 Pls3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pls3 NCBI NCBI:5358