Brms1 - breast cancer metastasis-suppressor 1 Gene
Species: Mus musculus
Gene Type: protein coding
Gene ID: 107392
Summary
Predicted to enable NF-kappaB binding activity and histone deacetylase binding activity. Predicted to be involved in several processes, including positive regulation of anoikis; positive regulation of protein deacetylation; and regulation of transcription, DNA-templated. Predicted to act upstream of or within apoptotic process. Predicted to be located in cytoplasm and nucleus. Predicted to be part of Sin3-type complex. Is expressed in alimentary system; central nervous system; genitourinary system; heart; and respiratory system. Orthologous to human BRMS1 (BRMS1 transcriptional repressor and anoikis regulator). [provided by Alliance of Genome Resources, Apr 2022]
Brms1 Products (3)
| mRNA | Protein | Name |
|---|---|---|
| NM_001374047.1 | NP_001360976.1 | breast cancer metastasis-suppressor 1 homolog isoform 1 |
| NM_001374048.1 | NP_001360977.1 | breast cancer metastasis-suppressor 1 homolog isoform 2 |
| NM_134155.3 | NP_598916.1 | breast cancer metastasis-suppressor 1 homolog isoform 1 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
12931191 | MGI |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
breast cancer metastasis-suppressor 1 homolog |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(12)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-144896 | FHT-1015 | Inhibitor | 98.41% | Unkown |
| HY-145946 | BRM/BRG1 ATP Inhibitor-2 | Inhibitor | 99.67% | Unkown |
| HY-148373 | BRM/BRG1 ATP Inhibitor-3 | Inhibitor | / | Unkown |
| HY-148374 | BRM/BRG1 ATP Inhibitor-4 | Inhibitor | / | Unkown |
| HY-178481 | BRM/BRG1 ATP-IN-5 | Inhibitor | / | Unkown |
| HY-178484 | BRM/BRG1 ATP-IN-6 | Inhibitor | / | Unkown |
| HY-178490 | BRM/BRG1 ATP-IN-8 | Inhibitor | / | Unkown |
| HY-180428 | BRM/BRG1 ATP degrader-1 | Degrader | / | Unkown |
| HY-183939 | L1-CIDE-BRM1-13 | / | Unkown | |
| HY-RS01626 | BRMS1 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS22408 | Brms1 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS28932 | Brms1 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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