Cyb5r3 - cytochrome b5 reductase 3 Gene

Also Known as B5R; Dia1; Dia-1; WU:Cyb5r3; 0610016L08Rik; 2500002N19Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 109754

Summary

Predicted to enable cytochrome-b5 reductase activity, acting on NAD(P)H and nucleotide binding activity. Predicted to contribute to nitrite reductase (NO-forming) activity. Predicted to be involved in nitric oxide biosynthetic process. Predicted to act upstream of or within Cholesterol biosynthetic process. Located in mitochondrial inner membrane. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and hemolymphoid system gland. Human ortholog(s) of this gene implicated in breast Cancer and methemoglobinemia. Orthologous to human CYB5R3 (cytochrome b5 reductase 3). [provided by Alliance of Genome Resources, Apr 2022]

Cyb5r3 Products (1)

mRNA Protein Name
NM_029787.3 NP_084063.1 NADH-cytochrome b5 reductase 3

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
23055941 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

NADH-cytochrome b5 reductase 3

  • diaphorase 1 (NADH)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-103061 Dehydro-ZINC39395747 Inhibitor 98.07% Unkown
HY-RS17849 Cyb5r3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03421 CYB5R3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24317 Cyb5r3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cyb5r3 NCBI NCBI:1727