Dehydro-ZINC39395747

Cat. No.: HY-103061 Purity: 99.20%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Dehydro-ZINC39395747 is a derivative of ZINC39395747. ZINC39395747 is a potent cytochrome b5 reductase 3 (CYB5R3) inhibitor with an IC₅₀ of 9.14 μM and a K_d of 1.11 μM. ZINC39395747 can increase NO bioavailability in vascular cells.

For research use only. We do not sell to patients.

Dehydro-ZINC39395747 Chemical Structure

CAS No. : 433248-87-4

Size	Price	Stock	Quantity
Solid + Solvent
10 mM * 1 mL in DMSO ready for reconstitution	USD 440	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 440	In-stock	Estimated Time of Arrival: December 31
Solid
5 mg	USD 400	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 680	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 1900	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 2900	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
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Description

Molecular Weight

291.35

Formula

C₁₂H₉N₃O₂S₂

CAS No.

433248-87-4

Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C(C=C(CSC1=NC2=CC=CC=C2O1)N3)NC3=S

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 10 mg/mL (34.32 mM; ultrasonic and adjust pH to 6 with HCl; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.4323 mL	17.1615 mL	34.3230 mL
5 mM	0.6865 mL	3.4323 mL	6.8646 mL
10 mM	0.3432 mL	1.7161 mL	3.4323 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.20%

Select Batch:

Data Sheet (269 KB) SDS (251 KB)

COA (249 KB) LCMS (98 KB)

Handling Instructions (2659 KB)

References

[1]. Rahaman MM, et al. Structure Guided Chemical Modifications of Propylthiouracil Reveal Novel Small Molecule Inhibitors of Cytochrome b5 Reductase 3 That Increase Nitric Oxide Bioavailability. J Biol Chem. 2015 Jul 3;290(27):16861-72. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.4323 mL	17.1615 mL	34.3230 mL	85.8074 mL
	5 mM	0.6865 mL	3.4323 mL	6.8646 mL	17.1615 mL
	10 mM	0.3432 mL	1.7161 mL	3.4323 mL	8.5807 mL
	15 mM	0.2288 mL	1.1441 mL	2.2882 mL	5.7205 mL
	20 mM	0.1716 mL	0.8581 mL	1.7161 mL	4.2904 mL
	25 mM	0.1373 mL	0.6865 mL	1.3729 mL	3.4323 mL
	30 mM	0.1144 mL	0.5720 mL	1.1441 mL	2.8602 mL