Mcf2 - mcf.2 transforming sequence Gene

Also Known as Dbl; Mcf-2; B230117G22Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 109904

Summary

Enables guanyl-nucleotide exchange factor activity. Acts upstream of or within cellular response to Leukemia Inhibitory Factor and dendrite development. Is expressed in femur; fibula; and tibia. Orthologous to human MCF2 (MCF.2 cell line derived transforming sequence). [provided by Alliance of Genome Resources, Apr 2022]

Mcf2 Products (7)

mRNA Protein Name
NM_001289730.2 NP_001276659.1 proto-oncogene DBL isoform 3
NM_001289731.1 NP_001276660.1 proto-oncogene DBL isoform 1
NM_001358998.1 NP_001345927.1 proto-oncogene DBL isoform 4
NM_001358999.1 NP_001345928.1 proto-oncogene DBL isoform 5
NM_001359000.1 NP_001345929.1 proto-oncogene DBL isoform 6
NM_001359001.1 NP_001345930.1 proto-oncogene DBL isoform 7
NM_133197.5 NP_573460.2 proto-oncogene DBL isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables guanyl-nucleotide exchange factor activity IDA
IDA: Inferred from direct assay
8464478 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
8464478 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: Inferred from expression pattern
20439489 MGI
acts upstream of or within dendrite development IMP
IMP: Inferred from mutant phenotype
11940671 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

proto-oncogene DBL

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-146756 22-((4-Methoxyphenyl)urea-1-yl)-22-deoxypleuromutilin Inhibitor / Unkown
HY-RS08222 MCF2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08223 MCF2L Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19145 Mcf2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22629 Mcf2l Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25636 Mcf2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mcf2 NCBI NCBI:4168