PLAAT3 - phospholipase A and acyltransferase 3 Gene

Homo sapiens

Also known as AdPLA; HRSL3; HRASLS3; HREV107; PLA2G16; PLAAT-3; H-REV107; HREV107-1; HREV107-3; H-REV107-1

Gene ID: 11145 | Gene type: protein coding

About PLAAT3

Cytogenetic location: 11q12.3-q13.1 Genomic coordinates (GRCh38): 11:63,574,462-63,616,927 (from NCBI)

This gene has 6 transcripts (splice variants), 221 orthologues and 7 paralogues. Biased expression in fat (RPKM 173.9), testis (RPKM 32.8) and 11 other tissues.

Summary

Enables N-acyltransferase activity; Phospholipase A1 activity; and Phospholipase A2 activity. Involved in N-acylphosphatidylethanolamine metabolic process. Predicted to be located in several cellular components, including lysosome; nuclear envelope; and peroxisome. Predicted to be active in cytoplasm. Biomarker of seminoma. [provided by Alliance of Genome Resources, Apr 2022]

PLAAT3 Products(2)

mRNA	Protein	Name
NM_001128203.2	NP_001121675.1	phospholipase A and acyltransferase 3
NM_007069.3	NP_009000.2	phospholipase A and acyltransferase 3

PLAAT3 Protein Structure

LRAT

0
100
162 a.a.

Protein Preferred Names

Protein Names

phospholipase A and acyltransferase 3

Ca-independent phospholipase A1/2

Recombinant PLAAT3 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71211	PLA2G16 Protein, Human (His)	P53816 (D12-D132)	≥95%

Related Diseases

Diseases

Alias

Poland Syndrome

Poland Anomaly	Poland Sequence
Poland Syndactyly	Poland'S Syndrome
Poland'S Anomaly	Poland'S Syndactyly
Acro-Pectoro-Renal Field Defect	Brachydactyly, Absent Pectoral Muscles And Agenesis/Hypoplasia Of Kidneys
Unilateral Defect Of Pectoralis Muscle And Syndactyly Of The Hand	Unilateral Defect Of Pectoralis Major And Syndactyly Of The Hand

Acute Flaccid Myelitis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10638	PLAAT3 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	PLAAT3	RGD	RGD:2829
Mus musculus	PLAAT3	MGD	MGI:2179715
Macaca mulatta	PLAAT3	VGNC	VGNC:76055
Canis familiaris	PLAAT3	VGNC	VGNC:57387

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