Dffa - DNA fragmentation factor subunit alpha Gene

Also Known as ICAD-S

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 114214

Summary

Predicted to enable deoxyribonuclease inhibitor activity; protein domain specific binding activity; and protein folding chaperone. Predicted to be involved in chaperone-mediated protein folding; negative regulation of deoxyribonuclease activity; and negative regulation of execution phase of Apoptosis. Predicted to act upstream of or within negative regulation of apoptotic DNA fragmentation; positive regulation of apoptotic process; and thymocyte apoptotic process. Located in nucleus. Orthologous to human DFFA (DNA fragmentation factor subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]

Dffa Products (2)

mRNA Protein Name
NM_001398977.1 NP_001385906.1 DNA fragmentation factor subunit alpha isoform 1
NM_053679.3 NP_446131.2 DNA fragmentation factor subunit alpha isoform 2
Protein Preferred Names Protein Names

DNA fragmentation factor subunit alpha

  • DNA fragmentation factor, alpha polypeptide

  • DNA fragmentation factor, alpha subunit

Orthologs Information

Species Symbol Source ID
Homo sapiens Dffa NCBI NCBI:1676