Acta1 - actin alpha 1, skeletal muscle Gene

Also Known as Acts; Acta-2; Actsk-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 11459

Summary

Predicted to enable ATP binding activity. Involved in skeletal muscle fiber development. Predicted to be located in actin Cytoskeleton and sarcomere. Predicted to be part of dynactin complex. Predicted to be active in actin filament; stress fiber; and striated muscle thin filament. Is expressed in several structures, including alimentary system; brain; genitourinary system; heart; and limb. Used to study nemaline myopathy 3. Human ortholog(s) of this gene implicated in congenital fiber-type disproportion and nemaline myopathy 3. Orthologous to human ACTA1 (actin alpha 1, skeletal muscle). [provided by Alliance of Genome Resources, Apr 2022]

Acta1 Products (2)

mRNA Protein Name
NM_001272041.1 NP_001258970.1 actin, alpha skeletal muscle
NM_009606.3 NP_033736.1 actin, alpha skeletal muscle

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15975910 MGI
Biological Process GO Annotation Evidence References Source
involved in skeletal muscle fiber development IDA
IDA: Inferred from direct assay
2731651 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

actin, alpha skeletal muscle

  • alpha-actin-1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00213 ACTA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22375 Acta1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28899 Acta1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Acta1 NCBI NCBI:58