Angpt2 - angiopoietin 2 Gene

Also Known as Ang2; Agpt2; Ang-2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 11601

Summary

This gene encodes an endothelial cell (EC)-derived regulator of angiogenesis and ligand for endothelial-specific receptor tyrosine kinase. The encoded protein acts as an anti-apoptotic factor for stressed ECs and a proapoptotic factor for resting ECs. [provided by RefSeq, Jan 2013]

Angpt2 Products (1)

mRNA Protein Name
NM_007426.4 NP_031452.2 angiopoietin-2 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
9204896 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within angiogenesis IGI
IGI: Inferred from genetic interaction
16778080 MGI
acts upstream of or within blood vessel morphogenesis IMP
IMP: Inferred from mutant phenotype
15579434 MGI
acts upstream of or within negative regulation of angiogenesis IDA
IDA: Inferred from direct assay
9204896 MGI
acts upstream of or within negative regulation of cell-substrate adhesion IDA
IDA: Inferred from direct assay
9846489 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

angiopoietin-2

Recombinant Angpt2 Proteins

Cat. No. Product Name Accession Purity
HY-P7844 Angiopoietin-2 Protein, Mouse (HEK293, Fc) O35608 (Y19-F496) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P72830 Angiopoietin-2 Protein, Mouse (HEK293, His) O35608 (K275-F496) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00688 ANGPT2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-117733 Zerumin A Inhibitor / Unkown
HY-RS16719 Angpt2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23155 Angpt2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Angpt2 NCBI NCBI:285