Aicda - activation-induced cytidine deaminase Gene

Also Known as Aid; Arp2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 11628

Summary

Enables cytidine deaminase activity. Involved in cytidine deamination and isotype switching. Acts upstream of or within cellular response to lipopolysaccharide and defense response to bacterium. Predicted to be part of protein-containing complex. Predicted to be active in P-body and nucleus. Is expressed in several structures, including immune system; lower urogenital tract; lung; reproductive system; and urethra epithelium. Human ortholog(s) of this gene implicated in hyperimmunoglobulin syndrome and immunodeficiency with hyper-IgM type 2. Orthologous to human AICDA (activation induced cytidine deaminase). [provided by Alliance of Genome Resources, Apr 2022]

Aicda Products (1)

mRNA Protein Name
NM_009645.2 NP_033775.1 single-stranded DNA cytosine deaminase
Protein Preferred Names Protein Names

single-stranded DNA cytosine deaminase

  • activation induced deaminase

  • cytidine aminohydrolase

Aicda Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Aicda Q9WVE0 Top2b Mus musculus Q64511
Anti Bait CoIP
21186367
Intra
Aicda Q9WVE0 Top2b Mus musculus Q64511
Anti Tag CoIP
21186367
Intra
Aicda Q9WVE0 Top2b Mus musculus Q64511
Pull Down
21186367
Cross
Aicda Q9WVE0 GADD45A Homo sapiens P24522
Anti Tag CoIP
23820005
Intra
Aicda Q9WVE0 Ptbp2 Mus musculus Q91Z31
Anti Bait CoIP
21186367
Intra
Aicda Q9WVE0 Ptbp2 Mus musculus Q91Z31
Pull Down
21186367
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant Aicda Proteins

Cat. No. Product Name Accession Purity
HY-P72074 AICDA Protein, Mouse (His-Myc) Q9WVE0 (M1-F198) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P10337 OXM-7 Agonist / Unkown
HY-RS00488 AICDA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19405 Aicda Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25897 Aicda Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Aicda NCBI NCBI:57379