Acacb - acetyl-CoA carboxylase beta Gene

Also Known as Acc2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 116719

Summary

Enables biotin binding activity. Involved in response to organic cyclic compound and response to xenobiotic stimulus. Located in mitochondrion. Used to study fatty liver disease. Orthologous to human ACACB (Acetyl-CoA Carboxylase beta). [provided by Alliance of Genome Resources, Apr 2022]

Acacb Products (1)

mRNA Protein Name
NM_053922.2 NP_446374.2 acetyl-CoA carboxylase 2 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables biotin binding IDA
IDA: Inferred from direct assay
12949377 RGD
Biological Process GO Annotation Evidence References Source
involved in D-glucose import IMP
IMP: Inferred from mutant phenotype
31709908 RGD
involved in fatty acid oxidation IMP
IMP: Inferred from mutant phenotype
31709908 RGD
involved in intracellular aspartate homeostasis IMP
IMP: Inferred from mutant phenotype
31709908 RGD
involved in intracellular glutamate homeostasis IMP
IMP: Inferred from mutant phenotype
31709908 RGD
involved in lactic acid secretion IMP
IMP: Inferred from mutant phenotype
31709908 RGD
involved in pentose-phosphate shunt IMP
IMP: Inferred from mutant phenotype
31709908 RGD
involved in purine nucleotide metabolic process IMP
IMP: Inferred from mutant phenotype
31709908 RGD
involved in regulation of cardiac muscle hypertrophy in response to stress IMP
IMP: Inferred from mutant phenotype
31709908 RGD
involved in response to nutrient IEP
IEP: Inferred from expression pattern
26394137 RGD
involved in response to nutrient levels IEP
IEP: Inferred from expression pattern
25943649 RGD
involved in response to organic cyclic compound IMP
IMP: Inferred from mutant phenotype
12842871 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
16979414 RGD
involved in tricarboxylic acid metabolic process IMP
IMP: Inferred from mutant phenotype
31709908 RGD
Cellular Component GO Annotation Evidence References Source
part of mitochondrial fatty acid beta-oxidation multienzyme complex IDA
IDA: Inferred from direct assay
31709908 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

acetyl-CoA carboxylase 2

  • acetyl-Coenzyme A carboxylase 2

  • acetyl-Coenzyme A carboxylase beta

Orthologs Information

Species Symbol Source ID
Homo sapiens Acacb NCBI NCBI:32