Slc25a5 - solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5 Gene

Also Known as Ant2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 11740

Summary

This gene encodes a transmembrane domain-containing protein that localizes to the mitochondrial inner membrane. The encoded protein facilitates the exchange of ADP from the cytoplasm with ATP from the mitochondria. Pseudogenes for this gene are found on multiple chromosomes. [provided by RefSeq, May 2015]

Slc25a5 Products (1)

mRNA Protein Name
NM_007451.4 NP_031477.1 ADP/ATP translocase 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables ATP:ADP antiporter activity IDA
IDA: Inferred from direct assay
31341297 MGI
enables ATP:ADP antiporter activity IMP
IMP: Inferred from mutant phenotype
31618756 MGI
enables oxidative phosphorylation uncoupler activity IDA
IDA: Inferred from direct assay
31341297 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
31618756 MGI
enables proton transmembrane transporter activity IDA
IDA: Inferred from direct assay
31341297 MGI
Biological Process GO Annotation Evidence References Source
involved in B cell differentiation IMP
IMP: Inferred from mutant phenotype
25613378 MGI
involved in adaptive thermogenesis IMP
IMP: Inferred from mutant phenotype
31341297 MGI
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: Inferred from expression pattern
20439489 MGI
involved in erythrocyte differentiation IMP
IMP: Inferred from mutant phenotype
25613378 MGI
involved in mitochondrial ADP transmembrane transport IDA
IDA: Inferred from direct assay
31341297 MGI
involved in mitochondrial ADP transmembrane transport IMP
IMP: Inferred from mutant phenotype
31618756 MGI
involved in mitochondrial ATP transmembrane transport IDA
IDA: Inferred from direct assay
31341297 MGI
involved in mitochondrial ATP transmembrane transport IMP
IMP: Inferred from mutant phenotype
31618756 MGI
involved in positive regulation of mitophagy IDA
IDA: Inferred from direct assay
31618756 MGI
involved in regulation of mitochondrial membrane permeability IMP
IMP: Inferred from mutant phenotype
31489369 MGI
Cellular Component GO Annotation Evidence References Source
located in mitochondrial inner membrane IDA
IDA: Inferred from direct assay
28376086 MGI
part of mitochondrial permeability transition pore complex IMP
IMP: Inferred from mutant phenotype
31489369 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ADP/ATP translocase 2

  • ADP, ATP carrier protein 2

  • adenine nucleotide translocase

  • adenine nucleotide translocator 2, fibroblast

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13131 SLC25A5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20216 Slc25a5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26723 Slc25a5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc25a5 NCBI NCBI:292