SLC25A5 - solute carrier family 25 member 5 Gene

Homo sapiens

Also known as T2; T3; 2F1; AAC2; ANT2

Gene ID: 292 | Gene type: protein coding

About SLC25A5

Cytogenetic location: Xq24 Genomic coordinates (GRCh38): X:119,468,444-119,471,396 (from NCBI)

This gene has 4 transcripts (splice variants), 202 orthologues and 49 paralogues. Ubiquitous expression in duodenum (RPKM 370.1), small intestine (RPKM 299.2) and 25 other tissues.

Summary

This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Suppressed expression of this gene has been shown to induce Apoptosis and inhibit tumor growth. The human genome contains several non-transcribed pseudogenes of this gene.[provided by RefSeq, Jun 2013]

SLC25A5 Products(1)

mRNA	Protein	Name
NM_001152.5	NP_001143.2	ADP/ATP translocase 2

SLC25A5 Protein Structure

Mito_carr

0
100
200
298 a.a.

Protein Preferred Names

Protein Names

ADP/ATP translocase 2

adenine nucleotide translocator 2 (fibroblast)

Related Diseases

Diseases

Alias

Oncocytoma

Oxyphilic Adenoma	Follicular Adenoma, Oxyphilic Cell
Adenoma, Oxyphilic	Hurthle Cell Tumor
Oncocytic Neoplasm

Hypertension And Brachydactyly Syndrome

Brachydactyly With Hypertension	Bilginturan Syndrome
HTNB	Brachydactyly-Arterial Hypertension Syndrome
Brachydactyly, Type E, With Short Stature And Hypertension	Bilginturan Brachydactyly
Brachydactyly Type E With Short Stature And Hypertension	Type E Brachydactyly With Short Stature And Hypertension
Brachydactyly Type E, With Short Stature And Hypertension	Hypertension With Brachydactyly

Dilated Cardiomyopathy

Familial Dilated Cardiomyopathy	Primary Dilated Cardiomyopathy
Idiopathic Dilated Cardiomyopathy	Congestive Cardiomyopathy
Idiopathic Dilation Cardiomyopathy	Primary Familial Dilated Cardiomyopathy
Cardiomyopathy, Dilated	DCM
Cardiomyopathy, Familial Dilated	Dilated Cardiomyopathy, Familial
Hypokinetic Dilated Cardiomyopathy, Familial	Familial Idiopathic Cardiomyopathy
Fdc	Cardiomyopathy, Familial Idiopathic
Idiopathic Cardiomegaly	Dilated Congestive Cardiomyopathy
Chronic Dilated Cardiomyopathy	Ccm - [Congestive Cardiomyopathy]
Cocm - [Congestive Cardiomyopathy]	Dcm - [Dilated Cardiomyopathy]
Dilated-Hypokinetic Cardiomyopathy	Congestive Idiopathic Cardiomyopathy
Primary Idiopathic Dilated Cardiomyopathy

Bubonic Plague

Black Death	Plague, Bubonic
Plague, Septicemic	Pestis Bubonica

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13131	SLC25A5 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	SLC25A5	VGNC	VGNC:54599
Rattus norvegicus	SLC25A5	RGD	RGD:620353
Bos taurus	SLC25A5	VGNC	VGNC:49966
Mus musculus	SLC25A5	MGD	MGI:1353496
Others	SLC25A5	NCBI

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