Klf16 - Kruppel-like factor 16 Gene

Also Known as DRRF; BTEB4

Species: Mus musculus

Gene Type: protein coding
Gene ID: 118445

Summary

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Acts upstream of or within Dopamine Receptor signaling pathway and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in several structures, including brain; embryo mesenchyme; genitourinary system; gut; and retina. Orthologous to human KLF16 (Kruppel like factor 16). [provided by Alliance of Genome Resources, Apr 2022]

Klf16 Products (1)

mRNA Protein Name
NM_078477.2 NP_510962.2 Krueppel-like factor 16

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
11390978 MGI
enables DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
11390978 MGI
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
11390978 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
11390978 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within G protein-coupled dopamine receptor signaling pathway IDA
IDA: Inferred from direct assay
11390978 MGI
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
11390978 MGI
acts upstream of or within regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
11390978 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

Krueppel-like factor 16

  • BTE-binding protein 4

  • basic transcription element-binding protein 4

  • dopamine receptor regulating factor

  • transcription factor BTEB4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07337 KLF16 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21582 Glis2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21618 Klf16 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28136 Klf16 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Klf16 NCBI NCBI:83855