Bdkrb1 - bradykinin receptor, beta 1 Gene

Also Known as B1R; BKR1; B1BKR; Bdkrb; BRADYB1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12061

About Bdkrb1

Chromosome 12: 105,569,344-105,571,687 forward strand.GRCm39:CM001005.3

This gene has 3 transcripts (splice variants), 147 orthologues, 9 paralogues and is associated with 17 phenotypes.

Summary

Enables peptide binding activity. Acts upstream of or within response to lipopolysaccharide. Predicted to be located in membrane and neuron projection. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and liver and biliary system. Human ortholog(s) of this gene implicated in end stage renal disease; hypertension; and pulmonary fibrosis. Orthologous to human BDKRB1 (Bradykinin Receptor B1). [provided by Alliance of Genome Resources, Apr 2022]

Bdkrb1 Products (1)

mRNA Protein Name
NM_007539.3 NP_031565.1 B1 bradykinin receptor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables peptide binding IDA
IDA: Inferred from direct assay
8602848 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within response to lipopolysaccharide IDA
IDA: Inferred from direct assay
8602848 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Bdkrb1 Protein Structure

7tmA_BK-1

7tmA_BK-1: cd15380 (36 - 329)

7tmA_BK-1

7tmA_BK-1: cd15380 (37 - 63)

7tmA_BK-1

7tmA_BK-1: cd15380 (78 - 103)

7tmA_BK-1

7tmA_BK-1: cd15380 (116 - 146)

7tmA_BK-1

7tmA_BK-1: cd15380 (159 - 180)

7tmA_BK-1

7tmA_BK-1: cd15380 (205 - 234)

7tmA_BK-1

7tmA_BK-1: cd15380 (249 - 279)

7tmA_BK-1

7tmA_BK-1: cd15380 (297 - 322)

  • 0
  • 100
  • 200
  • 300
  • 334 a.a.
Protein Preferred Names Protein Names

B1 bradykinin receptor

  • BK-1 receptor

  • kinin B1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P4676 Lys-(Des-Arg9,Leu8)-Bradykinin Antagonist 99.78% Unkown
HY-P4676A Lys-(Des-Arg9,Leu8)-Bradykinin TFA Antagonist / Unkown
HY-RS01454 BDKRB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01455 Bdkrb1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01456 Bdkrb1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Bdkrb1 NCBI NCBI:623