C4b - complement component 4B (Chido blood group) Gene

Also Known as C4; Ss

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12268

Summary

Predicted to enable carbohydrate binding activity and complement component C1q complex binding activity. Acts upstream of or within complement activation and immunoglobulin mediated immune response. Located in extracellular space. Is expressed in brain; liver; reproductive system; and retina. Used to study systemic lupus erythematosus. Human ortholog(s) of this gene implicated in autistic disorder; autoimmune disease (multiple); complement deficiency (multiple); and renal cell carcinoma. Orthologous to several human genes including C4B (complement C4B (Chido blood group)). [provided by Alliance of Genome Resources, Apr 2022]

C4b Products (1)

mRNA Protein Name
NM_009780.2 NP_033910.2 complement C4-B precursor
Protein Preferred Names Protein Names

complement C4-B

  • complement component 4 (within H-2S)

  • complement component 4B (Childo blood group)

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Phase
HY-P990091 Riliprubart Inhibitor 99.90% Phase 3
HY-P99905 Efdamrofusp alfa 99.89% Phase 3

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS18586 C4b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01746 C4B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18215 C4a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24692 C4a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25071 C4b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens C4b NCBI NCBI:721