Casp14 - caspase 14 Gene

Also Known as MICE; mini-ICE

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12365

Summary

Predicted to enable cysteine-type endopeptidase activity involved in execution phase of Apoptosis. Predicted to be involved in cornification. Predicted to act upstream of or within cell differentiation and proteolysis. Predicted to be located in several cellular components, including keratin filament; mitochondrion; and nucleoplasm. Predicted to be active in cytoplasm. Is expressed in embryo; epidermis; epidermis stratum corneum; and skin. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis. Orthologous to human CASP14 (Caspase 14). [provided by Alliance of Genome Resources, Apr 2022]

Casp14 Products (1)

mRNA Protein Name
NM_009809.5 NP_033939.1 caspase-14

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
is active in cornified envelope IDA
IDA: Inferred from direct assay
26644517 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

caspase-14

  • CASP-14

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-174458 MD-4251 Degrader / Unkown
HY-P11596 NOTA-Asp2-αvβ6L / Unkown
HY-RS01948 CASP14 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20533 Casp14 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27042 Casp14 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Casp14 NCBI NCBI:23581