Ccnd2 - cyclin D2 Gene

Also Known as cD2; Vin1; Vin-1; 2600016F06Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12444

Summary

Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity and protein kinase binding activity. Acts upstream of or within several processes, including adult locomotory behavior; cellular response to X-ray; and long-term memory. Located in cytoplasm and nucleus. Part of cyclin D2-CDK4 complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in ductal carcinoma in situ; invasive lobular carcinoma; prostate cancer; and transitional cell carcinoma. Orthologous to human CCND2 (cyclin D2). [provided by Alliance of Genome Resources, Apr 2022]

Ccnd2 Products (2)

mRNA Protein Name
NM_009829.3 NP_033959.1 G1/S-specific cyclin-D2
NM_009829.3 NP_033959.1 G1/S-specific cyclin-D2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
8033213 MGI
Biological Process GO Annotation Evidence Verweise Source
acts upstream of or within adult locomotory behavior IMP
IMP: Inferred from mutant phenotype
23714078 MGI
acts upstream of or within cellular response to X-ray IMP
IMP: Inferred from mutant phenotype
23714078 MGI
acts upstream of or within long-term memory IMP
IMP: Inferred from mutant phenotype
23714078 MGI
acts upstream of or within regulation of cell cycle IMP
IMP: Inferred from mutant phenotype
11809706 MGI
Cellular Component GO Annotation Evidence Verweise Source
part of cyclin D2-CDK4 complex IDA
IDA: Inferred from direct assay
7739547 MGI
located in nucleus IDA
IDA: Inferred from direct assay
12801993 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

G1/S-specific cyclin-D2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-124129 10074-A4 Inhibitor 98.22% Unkown
HY-184654 MR-39 / Unkown
HY-RS02124 CCND2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17697 Ccnd2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24159 Ccnd2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ccnd2 NCBI NCBI:894