Ccnf - cyclin F Gene

Also Known as CycF; Fbxo1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12449

Summary

Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Acts upstream of or within negative regulation of centrosome duplication; placenta development; and re-entry into mitotic cell cycle. Predicted to be located in cell junction and centriole. Predicted to be part of SCF ubiquitin Ligase complex and cyclin-dependent protein kinase holoenzyme complex. Predicted to be active in centrosome; cytoplasm; and nucleus. Is expressed in liver lobe; midbrain ventricular layer; olfactory cortex ventricular layer; and telencephalon ventricular layer. Orthologous to human CCNF (cyclin F). [provided by Alliance of Genome Resources, Apr 2022]

Ccnf Products (11)

mRNA Protein Name
NM_001409800.1 NP_001396729.1 cyclin-F isoform 1
NM_001409801.1 NP_001396730.1 cyclin-F isoform 2
NM_001409803.1 NP_001396732.1 cyclin-F isoform 5
NM_001409804.1 NP_001396733.1 cyclin-F isoform 6
NM_001409805.1 NP_001396734.1 cyclin-F isoform 7
NM_001409806.1 NP_001396735.1 cyclin-F isoform 8
NM_001409807.1 NP_001396736.1 cyclin-F isoform 9
NM_001409808.1 NP_001396737.1 cyclin-F isoform 9
NM_001409809.1 NP_001396738.1 cyclin-F isoform 3
NM_001409832.1 NP_001396761.1 cyclin-F isoform 10
NM_007634.5 NP_031660.3 cyclin-F isoform 4

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of centrosome duplication IMP
IMP: Inferred from mutant phenotype
20596027 MGI
acts upstream of or within placenta development IMP
IMP: Inferred from mutant phenotype
14993286 MGI
acts upstream of or within re-entry into mitotic cell cycle IMP
IMP: Inferred from mutant phenotype
14993286 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cyclin-F

  • G2/mitotic-specific cyclin-F

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02129 CCNF Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21305 Ccnf Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27824 Ccnf Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ccnf NCBI NCBI:899