Entpd5 - ectonucleoside triphosphate diphosphohydrolase 5 Gene

Also Known as Pcph; Cd39l4; mNTPase; NTPDase5; ER-UDPase; NTPDase-5

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12499

Summary

Enables guanosine-diphosphatase activity and uridine-diphosphatase activity. Involved in several processes, including positive regulation of glycolytic process; protein N-linked glycosylation; and regulation of phosphatidylinositol 3-kinase signaling. Located in endoplasmic reticulum. Is expressed in several structures, including genitourinary system; gut; hemolymphoid system gland; liver; and nose. Orthologous to human ENTPD5 (ectonucleoside triphosphate diphosphohydrolase 5 (inactive)). [provided by Alliance of Genome Resources, Apr 2022]

Entpd5 Products (4)

mRNA Protein Name
NM_001026214.2 NP_001021385.1 ectonucleoside triphosphate diphosphohydrolase 5 isoform b precursor
NM_001286049.1 NP_001272978.1 ectonucleoside triphosphate diphosphohydrolase 5 isoform b precursor
NM_001286058.1 NP_001272987.1 ectonucleoside triphosphate diphosphohydrolase 5 isoform b precursor
NM_007647.3 NP_031673.2 ectonucleoside triphosphate diphosphohydrolase 5 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables GDP phosphatase activity IDA
IDA: Inferred from direct assay
21074248 MGI
enables UDP phosphatase activity IDA
IDA: Inferred from direct assay
10369669 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of positive effect 'de novo' post-translational protein folding IMP
IMP: Inferred from mutant phenotype
21074248 MGI
involved in UDP catabolic process IDA
IDA: Inferred from direct assay
10369669 MGI
acts upstream of positive effect UDP-glucose metabolic process IMP
IMP: Inferred from mutant phenotype
21074248 MGI
acts upstream of positive effect protein N-linked glycosylation IMP
IMP: Inferred from mutant phenotype
21074248 MGI
Cellular Component GO Annotation Evidence References Source
NOT located in Golgi apparatus IDA
IDA: Inferred from direct assay
10369669 MGI
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
21074248 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ectonucleoside triphosphate diphosphohydrolase 5

  • CD39 antigen-like 4

  • GDPase ENTPD5

  • NTPDase 5

  • UDPase ENTPD5

  • guanosine-diphosphatase ENTPD5

  • nucleoside diphosphatase

  • uridine-diphosphatase ENTPD5

Recombinant Entpd5 Proteins

Cat. No. Product Name Accession Purity
HY-P76317 CD39L4/ENTPD5 Protein, Mouse (sf9, His) Q9WUZ9 (T19-S427) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04399 ENTPD5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19255 Entpd5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25744 Entpd5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Entpd5 NCBI NCBI:957