WTIP - WT1 interacting protein Gene

Homo sapiens

Gene ID: 126374 | Gene type: protein coding

About WTIP

Cytogenetic location: 19q13.11 Genomic coordinates (GRCh38): 19:34,481,758-34,512,304 (from NCBI)

This gene has 2 transcripts (splice variants), 196 orthologues and 2 paralogues. Broad expression in fat (RPKM 6.5), ovary (RPKM 5.4) and 23 other tissues.

Summary

Predicted to enable transcription corepressor activity. Involved in several processes, including negative regulation of hippo signaling; positive regulation of gene silencing by miRNA; and response to hypoxia. Acts upstream of or within gene silencing by miRNA. Located in P-body. [provided by Alliance of Genome Resources, Apr 2022]

WTIP Products(1)

mRNA	Protein	Name
NM_001080436.2	NP_001073905.1	Wilms tumor protein 1-interacting protein

WTIP Protein Structure

LIM

0
100
200
300
400
430 a.a.

Protein Preferred Names

Protein Names

Wilms tumor protein 1-interacting protein

Wilms tumor 1 interacting protein

Related Diseases

Diseases

Alias

Wilms Tumor 1

Nephroblastoma	Wilms Tumor
WT1	Wilms' Tumor
Bilateral Wilms Tumor	Wilms Tumor, Type 1
Wilms Tumor, Somatic	Adult Nephroblastoma
Wt1 Disorder	Renal Embryonic Tumor
Adult Kidney Wilms Tumor	Childhood Kidney Wilms Tumor
Nonanaplastic Kidney Wilms Tumor

Prolidase Deficiency

Hyperimidodipeptiduria	Imidodipeptidase Deficiency
Peptidase Deficiency	PD
Deficiency Of Prolidase	Imidodipeptiduria
Proline Dipeptidase Deficiency

Chromosome 19q13.11 Deletion Syndrome

19q13.11 Microdeletion Syndrome	Monosomy 19q13.11
Del(19)(Q13.11)

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15855	WTIP Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	WTIP	VGNC	VGNC:52261
Rattus norvegicus	WTIP	RGD	RGD:1306411
Mus musculus	WTIP	MGD	MGI:2141920