WTIP - WT1 interacting protein Gene
Species: Homo sapiens
About WTIP
This gene has 2 transcripts (splice variants), 196 orthologues and 2 paralogues. Broad expression in fat (RPKM 6.5), ovary (RPKM 5.4) and 23 other tissues.
Summary
Predicted to enable transcription corepressor activity. Involved in several processes, including negative regulation of hippo signaling; positive regulation of gene silencing by miRNA; and response to hypoxia. Acts upstream of or within gene silencing by miRNA. Located in P-body. [provided by Alliance of Genome Resources, Apr 2022]
WTIP Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_001080436.2 | NP_001073905.1 | Wilms tumor protein 1-interacting protein |
WTIP Protein Structure
LIM: LIM domain (225 - 279)
LIM: LIM domain (290 - 344)
LIM: LIM domain (350 - 414)
- 0
- 100
- 200
- 300
- 400
- 430 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
Wilms tumor protein 1-interacting protein |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Wilms Tumor 1 |
|
|
| Prolidase Deficiency |
|
|
| Chromosome 19q13.11 Deletion Syndrome |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS15855 | WTIP Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Bos taurus | WTIP | VGNC | VGNC:52261 |
| Rattus norvegicus | WTIP | RGD | RGD:1306411 |
| Mus musculus | WTIP | MGD | MGI:2141920 |
| Others | WTIP | NCBI |
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