Col6a3 - collagen, type VI, alpha 3 Gene

Also Known as Col6a-3

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12835

Summary

Predicted to be an extracellular matrix structural constituent conferring tensile strength. Located in extracellular matrix; extracellular space; and sarcolemma. Part of Collagen trimer. Is expressed in several structures, including brain meninges; cardiovascular system; embryo mesenchyme; genitourinary system; and musculoskeletal system. Used to study Ullrich congenital muscular dystrophy and congenital muscular dystrophy. Human ortholog(s) of this gene implicated in Ullrich congenital muscular dystrophy; dystonia 27; and muscular dystrophy. Orthologous to human COL6A3 (Collagen type VI alpha 3 chain). [provided by Alliance of Genome Resources, Apr 2022]

Col6a3 Products (2)

mRNA Protein Name
NM_001243008.1 NP_001229937.1 collagen alpha-3(VI) chain isoform 1 precursor
NM_001243009.1 NP_001229938.1 collagen alpha-3(VI) chain isoform 2 precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within neuron apoptotic process IDA
IDA: Inferred from direct assay
21459131 MGI
acts upstream of or within phosphatidylinositol 3-kinase/protein kinase B signal transduction IDA
IDA: Inferred from direct assay
21459131 MGI
acts upstream of or within response to UV IDA
IDA: Inferred from direct assay
21459131 MGI
Cellular Component GO Annotation Evidence References Source
part of collagen trimer IDA
IDA: Inferred from direct assay
24563484 MGI
located in extracellular matrix IDA
IDA: Inferred from direct assay
8806434 MGI
located in extracellular space IDA
IDA: Inferred from direct assay
10444069 MGI
located in sarcolemma IDA
IDA: Inferred from direct assay
16810681 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

collagen alpha-3(VI) chain

  • collagen alpha 3 chain type VI

  • collagen alpha3(VI)

  • procollagen, type VI, alpha 3

  • type VI collagen alpha 3 subunit

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02994 COL6A3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18560 Col6a3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25042 Col6a3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Col6a3 NCBI NCBI:1293