Cycs - cytochrome c, somatic Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13063

Summary

Enables heme binding activity. Acts upstream of or within several processes, including activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; hydrogen peroxide metabolic process; and regulation of protein binding activity. Located in cytosol and mitochondrion. Is expressed in several structures, including central nervous system; jaw; limb; metanephros; and spiral ligament. Human ortholog(s) of this gene implicated in cholangiocarcinoma; lung non-small cell carcinoma; pancreatic cancer; and thrombocytopenia. Orthologous to human CYCS (cytochrome c, somatic). [provided by Alliance of Genome Resources, Apr 2022]

Cycs Products (1)

mRNA Protein Name
NM_007808.5 NP_031834.1 cytochrome c, somatic

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables heme binding IDA
IDA: Inferred from direct assay
16757556 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c IMP
IMP: Inferred from mutant phenotype
10830166 MGI
acts upstream of or within apoptotic process IDA
IDA: Inferred from direct assay
16757556 MGI
acts upstream of or within hydrogen peroxide metabolic process IDA
IDA: Inferred from direct assay
16757556 MGI
acts upstream of or within regulation of protein binding IMP
IMP: Inferred from mutant phenotype
10830166 MGI
Cellular Component GO Annotation Evidence References Source
located in cytosol IDA
IDA: Inferred from direct assay
14657025 MGI
located in mitochondrion IDA
IDA: Inferred from direct assay
14623868 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cytochrome c, somatic

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Phase
HY-101212 Fadraciclib Inhibitor 99.77% Phase 2
HY-147298 Plogosertib Inhibitor 98.59% Phase 2
HY-10558 CYC-116 Inhibitor 99.05% Phase 1

Pre-clinical Phase

Bioactive Molecules (11)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-112403 (S)-Roscovitine Inhibitor 99.15% Unkown
HY-147646 CDK1/Cyc B-IN-1 98.47% Unkown
HY-RS03428 CYC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17636 Cyc1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-173600 CYCS-INPP4A PPI-IN-1 Inducer 99.97% Unkown
HY-N17698 Cyclogaleginoside B / Unkown
HY-RS03429 CYCS Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-30237S (R)-Roscovitine-d7 Inhibitor / Unkown
HY-RS20264 Cycs Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24096 Cyc1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26772 Cycs Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cycs NCBI NCBI:54205