1. Cell Cycle/DNA Damage
    Apoptosis
  2. CDK
    Apoptosis
  3. CDK1/Cyc B-IN-1

CDK1/Cyc B-IN-1 

Cat. No.: HY-147646
Handling Instructions

CDK1/Cyc B-IN-1 (Compound 5) is a selective CDK1/Cyc B complex inhibitor with an IC50 of 97 nM. CDK1/Cyc B-IN-1 triggers apoptosis and G2/M cell cycle arrest. CDK1/Cyc B-IN-1 shows broad-spectrum cytotoxic action against cancer cell lines.

For research use only. We do not sell to patients.

CDK1/Cyc B-IN-1 Chemical Structure

CDK1/Cyc B-IN-1 Chemical Structure

CAS No. : 2459916-56-2

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Description

CDK1/Cyc B-IN-1 (Compound 5) is a selective CDK1/Cyc B complex inhibitor with an IC50 of 97 nM. CDK1/Cyc B-IN-1 triggers apoptosis and G2/M cell cycle arrest. CDK1/Cyc B-IN-1 shows broad-spectrum cytotoxic action against cancer cell lines[1].

IC50 & Target

CDK1-Cyclin B

97 nM (IC50)

In Vitro

CDK1/Cyc B-IN-1 (Compound 5) shows cytotoxic activity with IC50 values of 5.33 ± 0.69 µM and 21.69 ± 1.04 µM against HCT-116 and WI-38, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

353.85

Formula

C14H12ClN3O2S2

CAS No.
SMILES

COC1=CC=C(C(OC)=C1)N2C(SC3=C2N=C(N=C3Cl)C)=S

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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CDK1/Cyc B-IN-1
Cat. No.:
HY-147646
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