Ddx6 - DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 Gene

Also Known as p54; rck; HLR2; mRCK/P54; 1110001P04Rik; C430015D01Rik; E230023J21Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13209

Summary

Predicted to enable mRNA binding activity and protein domain specific binding activity. Acts upstream of or within negative regulation of neuron differentiation and stem cell population maintenance. Located in P-body. Is expressed in several structures, including brain; early conceptus; neural tube; oocyte; and trunk somite. Orthologous to human DDX6 (DEAD-box helicase 6). [provided by Alliance of Genome Resources, Apr 2022]

Ddx6 Products (5)

mRNA Protein Name
NM_001110826.1 NP_001104296.1 probable ATP-dependent RNA helicase DDX6
NM_001357702.1 NP_001344631.1 probable ATP-dependent RNA helicase DDX6
NM_001357703.1 NP_001344632.1 probable ATP-dependent RNA helicase DDX6
NM_007841.4 NP_031867.1 probable ATP-dependent RNA helicase DDX6
NM_181324.3 NP_851841.2 probable ATP-dependent RNA helicase DDX6

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of neuron differentiation IMP
IMP: Inferred from mutant phenotype
25456498 MGI
acts upstream of neuron differentiation IMP
IMP: Inferred from mutant phenotype
25456498 MGI
acts upstream of or within stem cell population maintenance IMP
IMP: Inferred from mutant phenotype
25456498 MGI
Cellular Component GO Annotation Evidence References Source
located in P-body IDA
IDA: Inferred from direct assay
25456498 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
20014101 MGI
located in cytoplasmic ribonucleoprotein granule IDA
IDA: Inferred from direct assay
37083226 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

probable ATP-dependent RNA helicase DDX6

  • ATP-dependent RNA helicase p54

  • D-E-A-D (aspartate-glutamate-alanine-aspartate) box polypeptide 6

  • DEAD (aspartate-glutamate-alanine-aspartate) box polypeptide 6

  • DEAD box protein 6

  • DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 6

  • oncogene RCK homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03663 DDX6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20266 Ddx6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26774 Ddx6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ddx6 NCBI NCBI:1656