Ebf3 - early B cell factor 3 Gene

Also Known as O/E-2; mKIAA4201; 3110018A08Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13593

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within positive regulation of transcription, DNA-templated. Predicted to be located in nucleus. Is expressed in several structures, including central nervous system; embryo mesenchyme; future midbrain; genitourinary system; and retina. Orthologous to human EBF3 (EBF transcription factor 3). [provided by Alliance of Genome Resources, Apr 2022]

Ebf3 Products (3)

mRNA Protein Name
NM_001113414.1 NP_001106885.1 transcription factor COE3 isoform 2
NM_001113415.1 NP_001106886.1 transcription factor COE3 isoform 1
NM_010096.3 NP_034226.1 transcription factor COE3 isoform 3

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
12139918 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
12139918 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
12139918 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within positive regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
12139918 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
12139918 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcription factor COE3

  • EBF-3

  • OE-2

  • Olf-1/EBF-like 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04126 EBF3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08139 MAPRE3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20271 Ebf3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20568 Mapre3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26779 Ebf3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ebf3 NCBI NCBI:253738