Epor - erythropoietin receptor Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13857

Summary

Predicted to enable erythropoietin receptor activity and identical protein binding activity. Acts upstream of or within animal organ development and signal transduction. Predicted to be located in cytoplasm; external side of plasma membrane; and nuclear speck. Is expressed in several structures, including brain; egg cylinder; genitourinary system; germ layer; and heart and pericardium. Human ortholog(s) of this gene implicated in anemia; familial erythrocytosis 1; high grade glioma; polycythemia; and systemic lupus erythematosus. Orthologous to human EPOR (erythropoietin receptor). [provided by Alliance of Genome Resources, Apr 2022]

Epor Products (3)

mRNA Protein Name
NM_001411820.1 NP_001398749.1 erythropoietin receptor isoform 2
NM_001411821.1 NP_001398750.1 erythropoietin receptor isoform 3
NM_010149.4 NP_034279.3 erythropoietin receptor isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables erythropoietin receptor activity IDA
IDA: Inferred from direct assay
8341708 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
15953601 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within brain development IMP
IMP: Inferred from mutant phenotype
11807041 MGI
acts upstream of or within decidualization IDA
IDA: Inferred from direct assay
17300687 MGI
acts upstream of or within embryo development IDA
IDA: Inferred from direct assay
17300687 MGI
involved in erythropoietin-mediated signaling pathway IDA
IDA: Inferred from direct assay
8341708 MGI
acts upstream of or within heart development IMP
IMP: Inferred from mutant phenotype
11807041 MGI
acts upstream of or within signal transduction IDA
IDA: Inferred from direct assay
17300687 MGI
Cellular Component GO Annotation Evidence References Source
is active in plasma membrane IDA
IDA: Inferred from direct assay
8341708 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

erythropoietin receptor

  • EPO-R

Recombinant Epor Proteins

Cat. No. Product Name Accession Purity
HY-P73033 Erythropoietin receptor/EpoR Protein, Mouse (sf9, Fc) P14753 (A25-P249) ≥ 85%, as determined by reducing SDS-PAGE.
HY-P73034 Erythropoietin receptor/EpoR Protein, Mouse (HEK293, His) P14753 (A25-P249) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-18960 CHZ868 Inhibitor 98.69% Unkown
HY-W062700 STS-E412 Activator 99.72% Unkown
HY-RS04448 EPOR Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18356 Epor Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24835 Epor Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-108864 Epoetin alfa Agonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Epor NCBI NCBI:2057