Ewsr1 - Ewing sarcoma breakpoint region 1 Gene

Also Known as Ews; Ewsh

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14030

Summary

Predicted to enable RNA binding activity; identical protein binding activity; and transcription coregulator activity. Located in nucleus. Is expressed in several structures, including branchial arch; central nervous system; genitourinary system; hemolymphoid system gland; and sensory organ. Human ortholog(s) of this gene implicated in Ewing sarcoma. Orthologous to human EWSR1 (EWS RNA binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Ewsr1 Products (12)

mRNA Protein Name
NM_001283061.2 NP_001269990.1 RNA-binding protein EWS isoform 1
NM_001283062.2 NP_001269991.1 RNA-binding protein EWS isoform 3
NM_001283063.2 NP_001269992.1 RNA-binding protein EWS isoform 4
NM_001362612.1 NP_001349541.1 RNA-binding protein EWS isoform 5
NM_001362613.1 NP_001349542.1 RNA-binding protein EWS isoform 6
NM_001362614.1 NP_001349543.1 RNA-binding protein EWS isoform 7
NM_001362615.1 NP_001349544.1 RNA-binding protein EWS isoform 8
NM_001362616.1 NP_001349545.1 RNA-binding protein EWS isoform 9
NM_001362617.1 NP_001349546.1 RNA-binding protein EWS isoform 10
NM_001362618.1 NP_001349547.1 RNA-binding protein EWS isoform 11
NM_001362620.1 NP_001349549.1 RNA-binding protein EWS isoform 12
NM_007968.4 NP_031994.2 RNA-binding protein EWS isoform 2

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15917470 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
11555636 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

RNA-binding protein EWS

  • Ewing sarcoma homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-173364 EB-TCIP Inducer 99.58% Unkown
HY-154979 Anti-hepatic fibrosis agent 2 / Unkown
HY-RS04581 EWSR1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19681 Ewsr1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26174 Ewsr1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ewsr1 NCBI NCBI:2130