F2rl3 - coagulation factor II (thrombin) receptor-like 3 Gene

Mus musculus

Also known as PAR4

Gene ID: 14065 | Gene type: protein coding

About F2rl3

Chromosome 8: 73,488,508-73,490,502 forward strand.GRCm39:CM001001.3

This gene has 2 transcripts (splice variants), 194 orthologues, 16 paralogues and is associated with 2 phenotypes. Broad expression in spleen adult (RPKM 9.1), thymus adult (RPKM 4.3) and 2 other tissues.

Summary

This gene encodes a member of the Protease-activated Receptor subfamily, part of the G-protein coupled receptor 1 family of proteins. The encoded receptor is proteolytically processed to reveal an extracellular N-terminal tethered ligand that binds to and activates the receptor. This receptor plays a role in blood coagulation, inflammation and response to pain. Mice lacking a functional copy of this gene exhibit impaired platelet activation and prolonged bleeding times. [provided by RefSeq, Sep 2016]

F2rl3 Products(1)

mRNA	Protein	Name
NM_007975.4	NP_032001.2	proteinase-activated receptor 4 preproprotein

F2rl3 Protein Structure

7tmA_PAR4

0
100
200
300
396 a.a.

Protein Preferred Names

Protein Names

proteinase-activated receptor 4

PAR-4	coagulation factor II receptor-like 3
thrombin receptor-like 3

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Rare Diseases
HY-RS04640	F2RL3 Human Pre-designed siRNA Set A	/	Unkown
HY-RS04641	F2rl3 Mouse Pre-designed siRNA Set A	/	Unkown
HY-RS04642	F2rl3 Rat Pre-designed siRNA Set A	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	F2rl3	NCBI	NCBI:9002

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