Il2rg - interleukin 2 receptor subunit gamma Gene

Predicted to enable interleukin-15 receptor activity and interleukin-2 binding activity. Predicted to be involved in interleukin-15-mediated signaling pathway and positive regulation of phagocytosis. Predicted to act upstream of or within positive regulation of gene expression and positive regulation of lymphocyte differentiation. Predicted to be located in cell surface. Predicted to be part of receptor complex. Predicted to be active in external side of plasma membrane. Used to study X-linked severe combined immunodeficiency and combined T cell and B cell immunodeficiency. Human ortholog(s) of this gene implicated in X-linked severe combined immunodeficiency; combined T cell and B cell immunodeficiency; and severe combined immunodeficiency. Orthologous to human IL2RG (interleukin 2 receptor subunit gamma). [provided by Alliance of Genome Resources, Apr 2022]