Il4i1 - interleukin 4 induced 1 Gene

Also Known as H4; H-4; H46; LAO; Fig1; H-46; LAAO; mIL4I1; Fig1-ps

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14204

Summary

Enables L-amino-acid oxidase activity. Involved in negative regulation of T cell mediated immune response to tumor cell; positive regulation of regulatory T cell differentiation; and regulation of B cell differentiation. Acts upstream of or within aromatic amino acid family metabolic process. Located in lysosome. Orthologous to human IL4I1 (interleukin 4 induced 1). [provided by Alliance of Genome Resources, Apr 2022]

Il4i1 Products (1)

mRNA Protein Name
NM_010215.3 NP_034345.2 L-amino-acid oxidase precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables L-amino-acid oxidase activity IDA
IDA: Inferred from direct assay
15383589 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within aromatic amino acid metabolic process IDA
IDA: Inferred from direct assay
15383589 MGI
involved in negative regulation of T cell mediated immune response to tumor cell IDA
IDA: Inferred from direct assay
21469114 MGI
involved in negative regulation of T cell mediated immune response to tumor cell IMP
IMP: Inferred from mutant phenotype
28405502 MGI
involved in positive regulation of regulatory T cell differentiation IDA
IDA: Inferred from direct assay
25778793 MGI
involved in regulation of B cell differentiation IMP
IMP: Inferred from mutant phenotype
29288206 MGI
Cellular Component GO Annotation Evidence References Source
located in lysosome IDA
IDA: Inferred from direct assay
15383589 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

L-amino-acid oxidase

  • IL4-induced protein 1

  • histocompatibility 46

  • interleukin-4-induced protein 1

  • interleukin-four induced gene 1

  • interleukin-four induced gene-1 protein

  • interleukin-four induced protein-1

  • protein Fig-1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-174262 IL4I1-IN-1 Inhibitor 99.95% Unkown
HY-184554 ZY-MY-111 Inhibitor / Unkown
HY-RS06768 IL4I1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17465 Il4i1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23923 Il4i1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Il4i1 NCBI NCBI:259307