Fut4 - fucosyltransferase 4 Gene

Also Known as FAL; LeX; CD15; Ssea1; SSEA-1; FucT-IV

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14345

Summary

Predicted to enable 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity. Involved in positive regulation of leukocyte tethering or rolling. Located in cell periphery and cell surface. Is expressed in several structures, including ear; embryo ectoderm; extraembryonic component; genitourinary system; and gut. Orthologous to human FUT4 (fucosyltransferase 4). [provided by Alliance of Genome Resources, Apr 2022]

Fut4 Products (2)

mRNA Protein Name
NM_010242.3 NP_034372.1 alpha-(1,3)-fucosyltransferase 4
NM_010242.3 NP_034372.1 alpha-(1,3)-fucosyltransferase 4

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables alpha-(1->3)-fucosyltransferase activity IDA
IDA: Inferred from direct assay
11485743 MGI
Biological Process GO Annotation Evidence References Source
involved in lymphocyte migration into lymph node IMP
IMP: Inferred from mutant phenotype
11485743 MGI
involved in positive regulation of leukocyte tethering or rolling IMP
IMP: Inferred from mutant phenotype
10894166 MGI
involved in positive regulation of neutrophil migration IMP
IMP: Inferred from mutant phenotype
11485743 MGI
Cellular Component GO Annotation Evidence References Source
located in cell periphery IDA
IDA: Inferred from direct assay
16099728 MGI
located in cell surface IDA
IDA: Inferred from direct assay
15063176 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

alpha-(1,3)-fucosyltransferase 4

  • 3-fucosyl-N-acetyl-lactosamine epitope

  • 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase

  • Lewis x

  • alpha (1,3) fucosyltransferase, myeloid specific

  • alpha 1,3-fucosyltransferase

  • fuc-TIV

  • fucosyltransferase IV

  • galactoside 3-L-fucosyltransf

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05155 FUT4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21343 Fut4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27862 Fut4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fut4 NCBI NCBI:2526